Pharmaceutical product



Patented i i lay 8, 119235.

hit

"resin I seine;

RUDOLF BER-ENDES AND FRITZ LANGE. OE ELBFIP ELD, FARBENFAERIKEN' VGRTE.FRZEDB. BAYER AND (10., 0..

COLOGNE-ON-THE-R-HINE, GERMANY.

imvnn-nussnn, NEAR PHARMACEUTICAL PRODUCT.

No Drawing. Application. filed December To all whom it may concern Beknown that We, RunoLr Bnnnnnns end. FRITZ LANGE, citizens of Ge aany,residing at Elberfeld, Germany, have invented new and usefulImprovements in Pharmaceutical Products, oi which the following is :1specification.

Our invention relates to the production of a new and valuablepharmaceutical prodnot which can be obtained by treating with tannin e.yeast of any kind and origin e, g.

yeast of beer or yeast obtained in distillation. of spirits. Beforecarrying outthe reaction the yeast may previously undergo plasniolysis.

Our new product when used es an inter nel medicine does not effect thestomach and only acts when it comes into the intestines. It is ofspecial value when used in chronicel catu'rhel affections of theintestines, an average daily dose being from two to five grains. Itpossesses an agreeable taste.

In carrying out our invention practically we can proceed as follows, thepzirtsbeing 5 by weight: i,

F amp/I2 zl. parts of pressed yeast inin e about 10 parts of drymaterial are stirred together with parts of water and 8 parts of tanninfor 3 to 6 hours at :1 0 temperature of 45 to A)? T reaction mixture isthen exactly ralized with caustic soda and filtered off. The preeipitaleis again washed with water and filtered 2, 1921. Serial No 518,553.

oli, dried, pulverized an oral hours to 105-120 C.

Example 3-50 parts ofpressed yeast of beer are treated with parts-ofeoininoii salt and the liquefied product is then stirred to ier with anaqueous solution'of 8 parts i tannin for several hours at 40"? C Afterdece d heated "for sevdescribed pharmaceutical pi, uct being: chemicallya compound of tannin with yeast, which e greyish powder soluble withCllfilCllllJj/ in water and to ts greater part soluble in alkalies; andbe 55 ing a valuable remedy against chronical" cutnrrha affections-ofthe intestines, subull 7S described,

i testimony whereof we have hereunto set our hands in the presence of:two sub-'60v scribing Witnesses.

RUDOLF BERENDES. FRITZ L AN GE. Vitnesses Hens BntioKNEn, I 'Hnmn NNWEYL ND.

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